Hier folgen meine Quellen zur Frage von @sunsh1n3 weshalb eine Virusinfektion eine Autoimmunerkrankung auch heilen oder stoppen kann.
Da ist zum Beispiel das Buch einer der bedeutendsten Virologinnen unserer Zeit, Karin Mölling, es heisst «Viren – Supermacht des Lebens» und auf Seite 242 schreibt sie:
Zitat: Viren verursachen Abwehr gegen Viren. Dieser Satz gehört zu den wichtigsten dieses Buches zum Verständnis der Bedeutung von Viren.
Und Publikationen verweisen auch immer wieder auf diese Thematik, ein paar Beispiele:
Quelle: Multiple sclerosis and viruses (Bezahlartikel)
Zitat1: Fortunately things have changed, and now we know that viruses, or infectious agents in general, can both protect against, and cause, autoimmunity.
Zitat2: Persistent viral infections appear to be very common and will undoubtedly involve many yet unidentified human viruses. This virome is in dynamic equilibrium with the immune system, an equilibrium that is subtly influenced by a large number of host genetic and epigenetic variations. As a result, our virome most likely contributes both to protect us against, and to induce, autoimmunity.
Quelle: Protective Role of Infections and Vaccinations on Autoimmune Diseases (Bezahlartikel)
Zitat: …conversely, infections may protect from autoimmune diseases. This paradoxical effect has been demonstrated for a number of bacteria, viruses and parasites on a variety of spontaneous or experimentally induced animal models of autoimmune diseases…
Quelle: Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease
Zitat1: Viruses can vaccinate against autoimmune disease.
Zitat2: Viruses have been shown to be one of the environmental factors that are capable of precipitating autoimmune disease by a variety of possible mechanisms discussed here. On the other side of the coin, viruses have the potential to abrogate an ongoing autoimmune reaction by inducing apoptosis of autoreactive cells, by influencing cellular trafficking, or by immune suppression.
Quelle: Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms
Zitat: Viral infections are a major trigger of autoimmunity. Virus-induced autoimmunity is a multidirectional process. Current data suggests that viruses can initiate autoimmunity via several pathways including molecular mimicry, epitope spreading, bystander activation and/or immortalization of infected B cells. To the contrary, a growing evidence is supporting the protective role of viruses against autoimmunity [3], where viral infections lead to the activation of regulatory immune responses, consequently suppressing the development of autoimmune reactions.
Quelle: Microbes and Viruses Are Bugging the Gut in Celiac Disease. Are They Friends or Foes?
Zitat: FIGURE 1 Infectious agents that were suggested to induce (left side) or protect against (right side) intestinal celiac disease.
Es gibt z.B. Hinweise, dass es darauf ankommt, wann im Leben eines Menschen eine bestimmte Virus Infektion stattfindet damit der betroffene Mensch entweder krank oder geschützt wird.
Zitat2: it is likely that the early (infancy or early childhood) EBV exposure might play a protective role, while the later infection might trigger CD or have no impact on it at all.
Vor diesem Hintergrund wird einem plötzlich klar, weshalb eine antivirale Therapie auf eigene Faust gegen MS sehr gefährlich sein kann, denn unter Umständen geschieht genau das Gegenteil von dem was man sich erhofft.
Auch hier gilt: der Teufel liegt im Detail! Deshalb brauchen wir Grundlagenforschung.